Holmes' Sign
in Multiple Sclerosis
Holmes' Sign

More accurately known as Stewart-Holmes' sign after the two neurologists from whom it takes it's name. Thomas Grainger Stewart (1877-1957) an English neurologist and Gordon Morgan Holmes (1876-1965) an Irish neurologist.
Also known as the rebound phenomenon, this is a sign where an individual is unable to check a movement when passive resistance is suddenly released.
The patient is asked to push against the examiner's hand, with their own hand or foot. When the examiner removes his hand the patient is unable to react quickly enough to the removal of the resistance and the limb kicks out.
A positive result may indicate damage to the cerebellum region of the brain and could be indicative of such conditions as hypotonia or cerebellar ataxia.
References:
Multiple
Sclerosis Encyclopaedia
Free
Medical Dictionary
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