Cladribine for Multiple Sclerosis
Leustatin
Cladribine
Originally an anti-cancer drug used in the treatment of leukaemia. The injectable form of Cladribine has been trialled for MS but this did not show any change in relapse rate or any slowing of progression.
However, now there are trials underway of an oral form of Cladribine for relapsing/remitting MS and it seems that this drug may be able to reduce the number of lesions, reduce relapse rates and slow disability progression.
Cladribine is used to kill off cells in the immune system, similar to that of Alemtuzumab (campath). During trial reported side-effects included bone marrow suppression with reduced platelet count, fatigue, nausea, rash, headache and reduction of appetite. It also increase the risk of infection to some viruses.
Approved Use
Cladribine is not yet approved and is still undergoing trials.
Side Effects
It appears that Amitriptyline has an extensive list of possible side-effects which can include:
- Headaches
- Reduced Appetite
- Bone Marrow Suppression
- Reduced Platelet Count
- Nausea
- Hot Flushes
- Fatigue
DISCLAIMER: The content of this site does not represent a qualified medical opinion. It is simply the information amassed by an MS patient while trying to understand this condition. You should seek the advice of your medical practitioner or neurologist before trying any treatment you may read about on this site. I am not a doctor, I am a patient.
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