Tolterodine for Multiple Sclerosis
Detrusitol
Tolterodine Tartrate
Tolterodine Tartrate blocks muscarinic recptors in the muscles of the bladder wall. When these receptors are stimulated the bladder contracts and empties. By blocking, or limiting, the stimulation of these receptors the bladder muscles relax making the bladder more stable.
It works by preventing a natural body chemical called acetylcholine from acting on the cholinergic, or muscarinic, receptors. This helps the bladder wall to relax reducing unstable, involuntary contractions of the bladder.
Can be used in MS to help with urinary frequency, urinary urgency and incontinence, ®Detrusitol is a brand name for Tolterodine and is a newer drug than Oxybutynin but works in a similar fashion.
Side Effects
Possible side-effects can include:
- Dry mouth
- Abdominal pain
- Constipation
- Difficulty in passing urine
- Fluid retention
- Flatulence
- Pins and Needles (Paraesthesia)
- Fatigue
In addition to the above side-effects I have noticed one other which took a few days to develop. My urine is now dark green and smells quite noticeable of ... kippers of all things! I wouldn't mind but I can't stand kippers.
DISCLAIMER: The content of this site does not represent a qualified medical opinion. It is simply the information amassed by an MS patient while trying to understand this condition. You should seek the advice of your medical practitioner or neurologist before trying any treatment you may read about on this site. I am not a doctor, I am a patient.
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